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Determining Your Endometrial Cancer Treatment Plan
What Are My Treatment Options?
Your treatment will depend on the stage at which your endometrial cancer is diagnosed. It’s important to work with your healthcare team to develop the appropriate treatment plan for you.
Surgery
Surgery is the most common treatment for endometrial cancer, when possible, and may include:
- Total hysterectomy (removing the uterus, including the cervix)
- Radical hysterectomy (removing the uterus, tissues next to the uterus, and part of the vagina)
- Bilateral salpingo-oophorectomy (removing both ovaries and fallopian tubes)
- Lymph node dissection (removing the lymph nodes and checking a sample of tissue for signs of cancer)
Surgery can be used to:
- Determine the stage of endometrial cancer
- Debulk, or remove as much of the tumor as possible
Radiation
Some patients may be given radiation therapy that uses high-energy x-rays or other types of radiation to destroy cancer cells or keep them from growing.
Systemic Treatments for Endometrial Cancer
Systemic treatments are those that affect, or work throughout, the entire body.
- Chemotherapy
Your healthcare professional may also consider chemotherapy. This is a treatment for endometrial cancer that uses medication to stop the growth of cancer cells, either by destroying them or keeping them from dividing.
- Hormone Therapy
Hormone therapy involves removing or blocking hormones that can cause the cancer to grow.
- Targeted Therapy
Targeted therapy for endometrial cancer uses medication to identify and attack specific cancer cells. Healthcare professionals can use molecular biomarker testing to determine if you could benefit from a targeted therapy.
- Immunotherapy
Immunotherapy is a type of targeted therapy that may help a person’s own immune system better recognize and kill cancer cells. The immune system normally keeps itself from attacking the body’s healthy cells. It does so by using “checkpoint” proteins on immune cells, which act like switches that need to be turned on to start an immune response. Cancer cells turn these checkpoint proteins off to avoid getting attacked by the immune system. Immunotherapies can be used to treat some endometrial cancers by switching the immune response back on.
If you or a loved one are facing endometrial cancer, talk to a healthcare professional about treatment options, and learn more here about an immunotherapy for certain types of advanced or returned (recurrent) endometrial cancer.
Clinical Studies
Researchers are always looking for ways to improve upon and develop new treatments for cancer. To do this, they conduct clinical studies, which evaluate potential risks or side effects of treatments and how well they may work. Clinical studies often provide an opportunity to get early access to new therapies and can be considered an integral part of your treatment plan, not just a "last resort.” Learn more about clinical studies.
Click here for definitions of common gynecologic terms.
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